University of Colorado Buffaloes head football coach Deion Sanders remains optimistic about a quick return to coaching following another surgery for blood clots, announced on Tuesday, October 7, 2025. The 58-year-old Pro Football Hall of Famer and former MLB star underwent the procedure after experiencing issues in his foot, which he revealed after the Buffaloes’ recent loss to Texas Christian University.
Sanders, who faced life-saving bladder cancer surgery earlier this year, described the blood clot issue as hereditary and unrelated to his intense coaching schedule. Speaking to the media ahead of Colorado’s upcoming game against Iowa State, he expressed confidence in being back for practice as early as Wednesday after a roughly four-hour surgery. A social media post later showed him smiling from a hospital bed, signaling his positive outlook.
This is not Sanders’ first encounter with blood clots. In 2023, he had surgery on both legs to address clots, narrowly avoiding a foot amputation. Two years earlier, while coaching at Jackson State University, he lost two toes due to similar issues. The latest surgery marks his 14th procedure, a testament to his resilience amid ongoing health challenges.
Despite well-wishes from fans urging him to slow down, Sanders emphasized that the condition is beyond his control. “It’s hereditary, it is what it is,” he said, dismissing suggestions that his work pace contributed to the issue.
The Buffaloes, currently 2-4 overall and 0-3 in Big 12 play, are preparing to face a strong Iowa State team (5-1) at Folsom Field this Saturday. Sanders’ determination to return quickly underscores his commitment to leading the team through a challenging season.
